Ainsley(KelseyGunn)isamisanthropewhohatespeoplebutwhenshesuddenlyfindsherselfinisolationwithnoonetotalkto,sherealizeshowmuchsheactuallymissesconnection.EnterUlysses,adeadmouseinajar.Withalittlebitofloneliness,apinchofimagination,andamouse-sizedtuxedo,Ulyssesbecomeshertrainingwheelsinthisnewlydiscoveredworldoffriendship.