Nate,a19yearoldfilmstudent,andMargaret,a52yearoldspinster,arebestfriendsinanodd,quirky,totallyworkingkindofway...untilNate'saudaciousclassmateDarlasetshimuponadatewithJames.Nate'snewlifeshakesaparthisfriendshipwithMargaret,whogoesoffonherowntostartacareerasastand-upcomedian.